The Role of Photoprotection in Optimizing the Treatment of Atopic Dermatitis

Atopic dermatitis (AD) is a chronic inflammatory skin disease with an estimated prevalence of 10–15% in children and 2–10% adults. Clinically, there notable phenotypic variability driven by complex interaction between genetics, immune function, the environment. Impairment barrier plays significant role pathogenesis AD. The apparent beneficial effect sunlight patients atopic eczema questioned due to its capacity disrupt generate free radicals that can damage proteins, lipids, DNA. sum external factors individual exposed throughout their lifetime termed exposome. Environmental such as sun exposure, temperature, humidity contribute both AD flares regional variation. Literature on photoprotection very scarce. use adequate sunscreens ensure level required prevent photoaging cancer mitigate dysfunction, decrease inflammation, neutralize facial redness. Herein we discuss review UV radiation exposome etiology AD, well photoprotection.